Unveiling transcriptional mechanisms of B7-H3 in breast cancer stem cells through proteomic approaches
Summary: B7-H3, an immune checkpoint molecule, is prominently overexpressed in various solid tumors, correlating with poor clinical outcomes.Despite its critical role in promoting tumorigenesis, metastasis, and immune evasion, Body Spray the regulatory mechanisms governing B7-H3 expression, particularly in cancer stem cells (CSCs), remain elusive.I